Jorge J Castillo Selected Research

Bone Marrow Diseases (Bone Marrow Disease)

10/2021	Phase 1 study of ibrutinib and the CXCR4 antagonist ulocuplumab in CXCR4-mutated Waldenström macroglobulinemia.
1/2021	Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström Macroglobulinemia.
5/2017	Prospective, Multicenter Clinical Trial of Everolimus as Primary Therapy in Waldenstrom Macroglobulinemia (WMCTG 09-214).
3/2017	Genomics, Signaling, and Treatment of Waldenström Macroglobulinemia.

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Jorge J Castillo Research Topics

Disease

55	Waldenstrom Macroglobulinemia (Macroglobulinemia) 01/2022 - 07/2014
30	Neoplasms (Cancer) 11/2021 - 01/2012
28	Lymphoma (Lymphomas) 12/2022 - 03/2012
11	B-Cell Lymphoma (Lymphoma, B Cell) 12/2021 - 05/2014
11	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/2021 - 01/2011
10	Plasmablastic Lymphoma 01/2022 - 01/2010
9	Multiple Myeloma 12/2022 - 01/2012
9	Disease Progression 01/2020 - 01/2014
7	Non-Hodgkin Lymphoma (Lymphosarcoma) 12/2022 - 10/2010
6	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 02/2011
5	Hemorrhage 06/2021 - 04/2015
5	Paraproteinemias (Monoclonal Gammopathy) 11/2019 - 03/2016
5	Hodgkin Disease (Hodgkin's Disease) 03/2016 - 01/2012
5	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2016 - 02/2011
4	Bone Marrow Diseases (Bone Marrow Disease) 10/2021 - 03/2017
4	Atrial Fibrillation 12/2020 - 04/2015
4	Infections 10/2020 - 02/2011
4	Neutropenia 10/2020 - 02/2011
4	Anemia 11/2019 - 11/2016
3	Cardiac Arrhythmias (Arrythmia) 06/2021 - 04/2015
3	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2016 - 10/2014
2	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 12/2022 - 01/2016
2	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 11/2021 - 01/2015
2	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 01/2021 - 03/2011
2	Diarrhea 10/2020 - 01/2012
2	Peripheral Nervous System Diseases (PNS Diseases) 01/2017 - 07/2014
2	Chromosome Aberrations (Chromosome Abnormalities) 12/2016 - 01/2016
2	Thrombocytopenia (Thrombopenia) 11/2016 - 04/2015
2	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2016 - 02/2014
2	Hypovolemia 01/2016 - 01/2012
2	Primary Effusion Lymphoma 01/2016 - 06/2015
2	Hyponatremia 01/2016 - 01/2012
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 08/2015 - 06/2013
2	Lymphadenopathy 08/2013 - 03/2012
2	Leukemia 06/2013 - 05/2012
1	Monoclonal Gammopathy of Undetermined Significance 12/2022
1	Herpes Zoster 12/2022
1	Thromboembolism 01/2022
1	POEMS Syndrome (Syndrome, POEMS) 01/2022
1	Hemolytic Anemia 11/2021
1	Hypertension (High Blood Pressure) 12/2020
1	Contusions 10/2020
1	Pneumonia (Pneumonitis) 10/2020
1	Edema (Dropsy) 10/2020
1	Spasm (Spasms) 10/2020
1	Lung Injury 01/2020

Drug/Important Bio-Agent (IBA)

33	ibrutinibIBA 01/2022 - 03/2012
24	Immunoglobulin M (IgM)IBA 12/2022 - 10/2014
16	Rituximab (Mabthera)FDA Link 12/2022 - 10/2010
8	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 03/2012
6	Bortezomib (Velcade)FDA Link 01/2019 - 07/2014
5	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 07/2014
5	Monoclonal AntibodiesIBA 06/2021 - 02/2011
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 01/2011
4	ParaproteinsIBA 01/2022 - 10/2014
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 01/2011
3	Bendamustine Hydrochloride FDA Link 12/2022 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2020
3	venetoclaxIBA 01/2022 - 07/2015
3	zanubrutinibIBA 01/2022 - 10/2020
3	Hemoglobins (Hemoglobin)IBA 10/2021 - 05/2017
3	Proteasome InhibitorsIBA 06/2021 - 01/2020
3	Prednisone (Sone)FDA LinkGeneric 01/2021 - 01/2011
3	Vincristine (Oncovin)FDA LinkGeneric 01/2021 - 01/2011
3	idelalisibIBA 01/2017 - 01/2012
3	Biological ProductsIBA 05/2014 - 09/2013
2	Thalidomide (Thalomid)FDA Link 01/2022 - 12/2014
2	Etoposide (VP 16)FDA LinkGeneric 01/2022 - 01/2021
2	daratumumabIBA 01/2022 - 10/2020
2	Anaplastic Lymphoma KinaseIBA 12/2021 - 06/2015
2	ixazomibIBA 01/2020 - 01/2018
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 01/2018
2	AlbuminsIBA 01/2019 - 03/2011
2	6-bromo-2-naphthyl sulfate (BNS)IBA 01/2019 - 03/2016
2	Interleukin-6 (Interleukin 6)IBA 01/2018 - 01/2015
2	Immunoglobulin G (IgG)IBA 11/2016 - 07/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 04/2015 - 10/2014
2	ofatumumab FDA Link 05/2014 - 02/2011
1	src-Family KinasesIBA 01/2022
1	Immunomodulating AgentsIBA 01/2022
1	Carboplatin (JM8)FDA LinkGeneric 01/2022
1	Ifosfamide FDA LinkGeneric 01/2022
1	Lenalidomide (CC 5013)FDA Link 01/2022
1	A 419259IBA 01/2022
1	AgglutininsIBA 11/2021
1	ulocuplumabIBA 10/2021
1	pembrolizumabIBA 10/2021
1	Immunoglobulins (Immunoglobulin)IBA 01/2021
1	Cell-Free Nucleic AcidsIBA 01/2021
1	Enoxaparin (Lovenox)FDA LinkGeneric 12/2020
1	Proto-Oncogene Proteins c-hckIBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2020
1	Messenger RNA (mRNA)IBA 01/2020

Therapy/Procedure

40	Therapeutics 12/2022 - 10/2010
23	Drug Therapy (Chemotherapy) 01/2022 - 01/2010
3	Highly Active Antiretroviral Therapy (HAART) 02/2015 - 03/2012
2	Stem Cell Transplantation 12/2022 - 10/2014
2	Prostatectomy (Retropubic Prostatectomy) 01/2019 - 08/2015
1	Oral Administration 11/2021